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SUMMARY:The frontline of vaccine development - Professor Margaret Stanley\
 ; Professor Derek Smith\; Professor Jonathan Heeney. University of Cambrid
 ge
DTSTART:20200129T193000Z
DTEND:20200129T210000Z
UID:TALK138001@talks.cam.ac.uk
CONTACT:Lotte Elton
DESCRIPTION:Vaccines have saved millions of lives worldwide\, and are a ke
 y global health intervention. In this talk\, we are thrilled to have three
  eminent professors speaking\, all experts working to develop new vaccines
  for diseases such as influenza\, HPV and Ebola. Each speaker will give an
  insight into their work\, before coming together as a panel to discuss th
 e role of vaccination in the fight against infectious disease. \n\nOur spe
 akers: \n*Professor Margaret Stanley*\nEvery 2 minutes somewhere in the wo
 rld a woman dies of cervical cancer - cancer caused by infection with the 
 human papillomavirus (HPV) and is a preventable disease. Currently\, there
  are 3 prophylactic virus-like particle (VLP) vaccines being developed\, u
 sing sophisticated recombinant molecular techniques and protein expression
 . In this talk\, Professor Margaret Stanley shares her work on the human p
 apillomavirus and the current vaccination schemes for HPV. She is currentl
 y an Emeritus Professor of Epithelial Biology in the Department of Patholo
 gy\, Cambridge. She also serves as the President of the International Papi
 llomavirus Society (IPVS) and is very active in advocating for HPV vaccina
 tion. She sits on the Working Group for HPV vaccines advising the WHO Stra
 tegic Advisory group of Experts (SAGE). In 2010\, Professor Stanley was gi
 ven the Lifetime Achievement Award by the American Society for Colposcopy 
 and Cervical Pathology (ASCCP) for her contributions to cervical cancer an
 d cervical pre-cancers research.\n\n\n*Professor Derek Smith*\nIn his talk
 \, Professor Derek Smith will discuss his work on studying the evolution o
 f the influenza virus and other rapidly evolving pathogens. Professor Smit
 h is the director of the Centre for Pathogen Evolution here in Cambridge a
 s well as a research scientist in the Department of Virology at Erasmus Me
 dical Center Rotterdam. His work has proved salient for the development of
  vaccines for modern day epidemics. His experimental and mathematical work
  is currently being used to predict the evolution of the influenza virus\,
  and he works with the WHO to select the composition of the influenza vacc
 ine (each year).\n\n\n*Professor Jonathan Heeney*\nJonathan Heeney is Head
  of The Laboratory of Viral Zoonotics. His research focuses on cross speci
 es transmissions of viruses\, and the co-evolution of viruses and their ho
 sts including the evolution of immune mechanisms of disease protection in 
 naturally infected but disease resistant species. Not only has this intere
 st led to the discovery of a number of new viruses\, but also genetic comp
 arison of host and viral sequences from the same individual.\nCurrently hi
 s laboratory applies these molecular technologies to gain an understanding
  of successful host immune responses to RNA viruses. Translationally this 
 information is utilized for the rational design of novel vaccines for the 
 prevention of diseases caused by notoriously complex viral pathogens. Heen
 ey is also the CEO of DIOSynVax Ltd\, a Cambridge University spin-out that
  has brought cutting edge technologies together into an exciting new platf
 orm that will significantly accelerate vaccine development and will achiev
 e dramatic improvements to the breadth of protection conferred by vaccines
  against emerging and re-emerging pathogens. This new vaccine accelerator 
 technology DIOS (Digitally designed\, Immune Optimised and Selected) is ba
 sed on outbreak sequence data to generate synthetic optimised vaccine inse
 rts to stimulate the broadest possible protection to limit future outbreak
 s of variable pathogens.\n\n\n**********************\nEveryone is welcome!
  \n\nThis event forms part of our 2020 University of Cambridge Global Heal
 th lecture series\, featuring a range of lectures and panels delving into 
 current issues in global health. \n\n\nAccess information:\nThe Divinity S
 chool has a ramped entrance so there is step-free access to the venue. \n
LOCATION:Main Lecture Theatre\,  Old Divinity School\,  St John’s Colleg
 e
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