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SUMMARY:SynBio Forum: New Sensors for Living Systems - Karen Polizzi - Kar
 en Polizzi\, Imperial College London
DTSTART:20200224T173000Z
DTEND:20200224T203000Z
UID:TALK140014@talks.cam.ac.uk
CONTACT:Stephanie Norwood
DESCRIPTION:SynBio Forum with George Malliaras and Karen Polizzi\n\nThis t
 erm's SynBio Forum will focus on biosensors and their applications\; from 
 neuroscience to pharmaceuticals. We have two very exciting speakers who wi
 ll discuss the use of organic electronic materials and genetically encoded
  sensors in bioscience research. As usual\, the talks will be followed by 
 a dinner buffet and drinks reception. Be sure to reserve your spot!\n\nPut
 ting the 'Bio' Back in Biosensing\n\nKaren Polizzi\, Reader in Biotechnolo
 gy\, Department of Chemical Engineering\, Imperial College London\n\nWhat 
 are in vivo biosensors? Most classical biosensors (like those used in bloo
 d sugar monitoring) rely on electrochemistry to convert the concentration 
 of a molecule of interest into a digital display. However\, there are a wh
 ole class of biosensors that are entirely genetically-encoded either by fu
 sing a transcriptional element that detects the molecule of interest to a 
 reporter protein like GFP or through proteins that have the ability to sen
 se the molecule and convert the concentration into an output. These geneti
 cally-encoded sensors are convenient tools for monitoring what is going on
  inside living cells since they don't require the addition of exogenous re
 agents or abiotic elements. We use sensors like these to monitor cellular 
 behaviour under different conditions. They can be used in conjunction with
  external stimuli (e.g. changing medium cells are fed) to control cellular
  behaviour.\n\nMore information\, abstracts\, and FREE registration via:\n
 https://www.eventbrite.co.uk/e/synbio-forum-new-sensors-for-living-systems
 -tickets-95221801973
LOCATION:Old Divinity School\, St Johns Street\, Cambridge
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