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SUMMARY:Porous Scaffolds for Osteoarticular Tissue Repair - Ms Meera Arumu
 gam\, Cambridge Centre for Medical Materials
DTSTART:20081013T100000Z
DTEND:20081013T103000Z
UID:TALK14547@talks.cam.ac.uk
CONTACT:Meera Arumugam
DESCRIPTION:Scaffolds can be used for tissue engineering either on their o
 wn or as delivery vehicles for autologous cells isolated from the circulat
 ion and bone marrow. Present research in the area aims to use porous\, bio
 active matrices as hosts for living cells. In the case of biomaterials use
 d for orthopaedic applications\, a bioactive matrix is required for the do
 nor mesenchymal stem cells\, obtained from bone and marrow\, to exhibit ph
 enotypic characteristics of bone cells and to develop strong adhesion to t
 he porous matrix. This talk will give a brief overview of the range of cer
 amic and composite scaffolds\, both dense and porous\, which are used or c
 an potentially be used in the field of musculoskeletal tissue engineering.
  Recent work done by the author incorporating various relevant human cell 
 types\, including osteoblasts\, chondrocytes and marrow-derived stromal ce
 lls\, into a range of porous biomaterials will also be presented. Most rec
 ently\, promising results have been obtained incorporating human embryonic
  stem cells into porous bioactive glass and collagen-GAG matrices in short
 -term culture and these will be described.
LOCATION:Cripps Court\, Magdalene College
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