BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Stochasticity and bistability in the lac operon - Dr Nicholas Ross
  (CUED)
DTSTART:20081114T140000Z
DTEND:20081114T150000Z
UID:TALK14898@talks.cam.ac.uk
CONTACT:Dr Guy-Bart Stan
DESCRIPTION:The _lac_ operon\, an extensively studied genetic regulatory s
 ystem\, is responsible for regulating the metabolism of lactose in _Escher
 ichia coli_. Existing models of the _lac_ operon are in the most part dete
 rministic\, and have sought to describe the nature of induction in the ope
 ron by means of the bistability which arises in the non-linear determinist
 ic models used. A model is derived using published as well as experimental
  data\, and it is shown by means of a hybrid stochastic simulation algorit
 hm that bimodality during induction results from the stochastic nature of 
 the _lac_ operon. Deterministic models\, and hence bistability\, are not a
 ble to predict the behaviour of the operon.
LOCATION:Cambridge University Engineering Department\, Lecture Room 3B
END:VEVENT
END:VCALENDAR