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SUMMARY:Computational Neuroscience Journal Club - Yashar Ahmadian
DTSTART:20200630T153000Z
DTEND:20200630T170000Z
UID:TALK149803@talks.cam.ac.uk
CONTACT:Jake Stroud
DESCRIPTION:Please join us for our fortnightly journal club online via zoo
 m where two presenters will jointly present a topic together.\n\nZoom info
 :\nhttps://us02web.zoom.us/j/82267089859?pwd=WXpTMzNadHZDQnZkQWtrcFVqMk9KU
 T09\nMeeting ID: 822 6708 9859\nPassword: 223170\n\nThe next topic is 'sen
 sory-motor integration in V1' presented by Yashar Ahmadian and Elliott Abe
 . Here is a brief summary of the journal club:\n\nIn the textbook view\, t
 he activity in the primary visual cortex is assumed to primarily represent
  the current visual stimulus. This simplification has been especially chal
 lenged by various studies of the past decade in mouse V1\, indicating that
  various contextual and motor-behavioral variables strongly affect V1 acti
 vity and explain much of its variance. \nA famous example is the amplifica
 tion of V1 responses during locomotion. Several findings indicate that the
  effect of locomotion on V1 is more complex than just a global change of g
 ain\, and should be viewed in the broader context of sensory-motor integra
 tion. An animal's self-motion has sensory consequences that tend to be hig
 hly predictable (e.g. self-motion causes optic flow). The brain can in pri
 nciple build an internal model of these "reafference signals"\, and use "e
 fference copies" of its own motor commands in order to filter out those pr
 edictable consequences so that neural responses (in at least a subset of n
 eurons) can represent the less predictable and more relevant aspects of ex
 ternal sensory inputs -- or so goes (one interpretation of) one specific f
 lavor of the predictive coding hypothesis. In this JC we will review some 
 of the evidence for such predictive coding in mouse V1 and the circuit mec
 hanisms implementing it.  \n \nWe (my student Elliott Abe and I) will focu
 s on these papers: \n- https://www.biorxiv.org/content/10.1101/2020.03.25.
 008607v1\n- https://linkinghub.elsevier.com/retrieve/pii/S0092-8674(17)305
 83-4\n- (time allowing) https://www.sciencedirect.com/science/article/pii/
 S0896627317307791\n\n\n
LOCATION:Online on Zoom
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