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SUMMARY:Session 2 - PLENARY TALK by Ruth Bowness - University of St. Andre
 ws - Modelling within-host tuberculosis infection using a hybrid multiscal
 e individual-based model - 
DTSTART:20200708T110000Z
DTEND:20200708T120000Z
UID:TALK149845@talks.cam.ac.uk
CONTACT:INI IT
DESCRIPTION:<span><a target="_blank" rel="nofollow"></a><a target="_blank"
  rel="nofollow"><i>Tuberculosis (TB) is an infectious disease caused by My
 cobacterium tuberculosis. Despite significant recent advances\, TB is the 
 biggest infectious killer globally - someone dies from the disease every 1
 8 seconds. I will describe a hybrid multiscale individual-based model that
  has been developed to study disease progression and treatment in the huma
 n lung. The model contains discrete agents which model the spatio-temporal
  interactions (migration\, binding\, killing etc.) of bacteria and immune 
 cells. Chemokine and oxygen dynamics are also included\, as well as Pharma
 cokinetic/Pharmacodynamic models\, which are incorporated into the model v
 ia PDEs. In this work\, I explore concepts of relapse and latent TB diseas
 e\, and their effect on treatment outcome.</i></a></span>  <br><br><br><br
 ><br>
LOCATION:Seminar Room 1\, Newton Institute
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