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SUMMARY:Cone subtype specification in human retinal organoids - Dr Robert 
 Johnston\, Department of Biology\, Johns Hopkins University\, Baltimore
DTSTART:20210121T140000Z
DTEND:20210121T150000Z
UID:TALK150562@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION: In humans\, three subtypes of cone photoreceptors enable tric
 hromatic color and high acuity vision. To overcome the challenges associat
 ed with studies of human development\, we utilized a human organoid system
  that recapitulates retinal development and photoreceptor specification. W
 e found that spatiotemporal regulation of thyroid hormone and retinoic aci
 d signaling specifies cone subtypes in human retinal organoids. Our studie
 s advanced human retinal organoids as a model for revealing mechanisms of 
 human development\, with promising utility for therapeutics and vision rep
 air.
LOCATION:Zoom meeting
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