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SUMMARY:A V Hill Lecture - Kings and Queens of the Mountain: Studies of Ex
 treme Physiology in Himalayan Sherpas - Dr Andrew Murray\, Metabolic Physi
 ology\, Department of Physiology\, Development and Neuroscience
DTSTART:20210302T000000Z
DTEND:20210302T000100Z
UID:TALK151228@talks.cam.ac.uk
CONTACT:Beverley Larner
DESCRIPTION:As we ascend to high altitude\, our bodies experience low oxyg
 en availability - a condition known as hypoxia. In response\, our heart ra
 te and breathing rate are adjusted in an attempt to maintain oxygen supply
  to our vital organs\, whilst levels of oxygen-carrying red cells increase
  in our blood. Despite this\, we are limited by the low oxygen available t
 o us\, and this impacts on our ability to think and exercise. In human pop
 ulations that have spent thousands of years residing at altitude\, such as
  the Himalayan Sherpas\, there has been a selection of genetic variations 
 which enable them to live\, work and reproduce in this environment. In thi
 s talk\, Andrew Murray will discuss work that he has carried out for more 
 than 15 years and across two major research expeditions in collaboration w
 ith the Xtreme Everest Research Group. Andrew will look at some of the par
 adoxes of our own bodies' responses to altitude\, and consider the differe
 nt evolutionary strategies adopted by Sherpas and other high-altitude dwel
 ling people. Finally\, Andrew will describe how this research is beginning
  to help in the treatment of patients who are experiencing hypoxia in othe
 r life-threatening contexts\, such as the intensive care unit.  
LOCATION:https://youtu.be/keEFh3za-Eo
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