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SUMMARY:The chromatin response of human cells to SARS-CoV-2 et al - Dr Rit
 wick Sawarkar\; Group Leader\, MRC Toxicology Unit\, University of Cambrid
 ge
DTSTART:20210331T140000Z
DTEND:20210331T150000Z
UID:TALK152053@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:A variety of environmental stressors and infections cause glob
 al transcriptional downregulation in human cells\, a phenomenon we termed 
 as Stress-Induced Transcriptional Attenuation (SITA). In the talk\, I will
  discuss our work on understanding the mechanism underlying SITA that has 
 led us to uncover novel nuclear condensates formed by liquid-liquid phase 
 separation. Similar transcriptional downregulation is also seen in lung ce
 lls upon SARS-CoV-2 infection\, identifying therapeutic avenues.\n\nPlease
  click here to join the webinar live: https://zoom.us/j/94864392896
LOCATION:Zoom Seminar
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