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SUMMARY:The actin cortex in live cells - Matthieu Piel - Matthieu Piel - I
 nstitute Curie
DTSTART:20201119T143000Z
DTEND:20201119T153000Z
UID:TALK154165@talks.cam.ac.uk
CONTACT:Margarida Rodrigues
DESCRIPTION:CPB Seminar\nMatthieu Piel - Institute Curie (Paris)\n\nA thin
  meshwork of actin filaments form below the plasma membrane\, forming the 
 cell outer layer also called the cell cortex. This layer produces forces t
 o shape cells and make them motile. Its central function in cell morphogen
 esis justified intense studies for now several decades. The quantity of ac
 cumulated knowledge about that structure is thus now huge. Nevertheless\, 
 because it is very thin and dense\, detailed observations of the actin cor
 tex in live cells have been limited and the assembly of actin structures h
 ave mostly been observed in vitro. Here I will describe what we learned us
 ing two novel approaches: 1) observing the actin cortex as it forms on the
  bare membrane of a stable bleb induced by cell confinement and 2) pinchin
 g the cortex in live cells between two magnetic beads to measure its thick
 ness and mecanical properties.\n\n\nRegister here\nhttps://us02web.zoom.us
 /webinar/register/WN_6Af3wv7FQJaoPpwXYs-35g
LOCATION:Zoom
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