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SUMMARY:Designer tissues: synthetic\, living and hybrid materials. - Profe
 ssor Hagan Bayley\, Professor of Chemical Biology\, University of Oxford.
DTSTART:20210225T160000Z
DTEND:20210225T170000Z
UID:TALK155671@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:By 3D printing\, we have assembled synthetic tissues comprisin
 g patterned networks of thousands of aqueous droplets joined by lipid bila
 yers. The droplets communicate with each other and with the environment th
 rough engineered protein pores. To mimic tissues\, the synthetic networks 
 should be endowed with various properties including the ability to store a
 nd use energy\, to move and change shape\, to detect signals\, to carry ou
 t computations and take up and release molecules. To a modest degree\, the
 se goals have been achieved. A related printing technology has been used t
 o pattern a variety of living cells\, providing structures that include sm
 all tumours and fragments of neural tissue. The mm-scale printed structure
 s can be used as building blocks for cm-scale structures ranging from synt
 hetic axons to hybrid constructs containing both synthetic and living cell
 s. An important goal is to communicate with these constructs by using exte
 rnal stimuli\, have them process the incoming signals and accordingly prod
 uce useful outputs for applications in medicine.
LOCATION:Meeting ID: 837 8058 8985 Passcode: 428653
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