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SUMMARY:CRISPR Cas Genome Editors - from Bacteria to Biotech - Prof Martin
  Jínek (Department of Biochemistry\, University of Zürich)
DTSTART:20210225T181500Z
DTEND:20210225T194500Z
UID:TALK155710@talks.cam.ac.uk
CONTACT:Miroslava Novoveska
DESCRIPTION:Link to join the YT live stream:\n\nhttps://youtu.be/znlX1p3Tu
 bs\n\nThe CRISPR-Cas system constitutes a genome defence mechanism that pr
 otects bacteria from invasive genetic elements such as viruses. The system
  functions by using guide RNA molecules in conjunction with programmable n
 ucleases such as Cas9 to recognize and cleave invader DNA. CRISPR-associat
 ed nucleases have been repurposed as powerful tools for precision genome e
 diting in eukaryotic cells and organisms. My research aims to elucidate th
 e molecular mechanisms of CRISPR-associated nucleases using a combination 
 of structural\, biochemical and biophysical approaches. These studies prov
 ide the foundation for understanding the molecular function of CRISPR geno
 me editors and for the ongoing development of CRISPR-based genome editing 
 for biotechnological and therapeutic applications.
LOCATION:Online
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