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SUMMARY:Mapping B Vitamin biosynthesis pathways in novel  lineages of the 
 Stramenopiles - Dominic Absolon
DTSTART:20210203T130000Z
DTEND:20210203T140000Z
UID:TALK156517@talks.cam.ac.uk
CONTACT:Dr Qi Wang
DESCRIPTION:Over the last decade or two\, advancements in sequencing techn
 ologies\, principally meta-barcoding and metagenomics\, have revealed a mi
 ssing microbial majority in the ocean biome. These novel linages of microb
 es play an important role in biogeochemical cycling and are at the basis o
 f the oceanic food web. However\, with the exception of a handful of cases
  their role in the community they live in is poorly understood\, not helpe
 d by the fact many of these novel lineages are currently unculturable. In 
 this project we are attempting to illuminate possible microbial interactio
 ns based on B vitamin exchange by utilising recent sequencing efforts. By 
 identifying present and absent B vitamin biosynthesis pathways we can begi
 n to understand why certain microbes might interact. The project is using 
 a sequence similarity approach (BLAST and protein domain annotation) to id
 entify known biosynthesis genes in novel lineages of the Stramenopile supe
 r group of the Eukaryotic tree of life. The diversity within this group al
 lows us to study a wide range of lifestyles and habitats and ultimately ex
 ploring how and why B vitamin auxotrophy might occur.
LOCATION:You can sign up at  https://lists.cam.ac.uk/mailman/listinfo/plan
 tsci-bioinfo . Zoom link will be sent to this list on the day of the meeti
 ng.
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