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SUMMARY:Recurrent problems in spinal-cord and cerebellar circuits - Dr Ste
 ve Edgley\, Physiology\, Development and Neuroscience
DTSTART:20210216T160000Z
DTEND:20210216T170000Z
UID:TALK156940@talks.cam.ac.uk
CONTACT:Dr Dervila Glynn
DESCRIPTION:Theme: *Neurons\, Circuits & Networks*\n\nOne of the best esta
 blished recurrent inhibitory pathways is the recurrent inhibition of mamma
 lian motoneurons through Renshaw cells.  Golgi cells form an inhibitory fe
 edback circuit in the granular layer of cerebellum. Feedback inhibitory pa
 thways are long established "textbook" elements of neural circuitry\, but 
 in both cases their functional role has not been well established. Here I 
 will present some new observations on the function of recurrent inhibition
  in the spinal-cord\, supporting the idea that this connection frequency t
 unes transmission of inputs through motoneurons. Secondly\, I will discuss
  evidence that the function of Golgi cells  is much more complex than clas
 sical studies based on circuit connectivity suggest. \n\nSteve is a Reader
  in the Department of Physiology\, Development and Neuroscience and a Fell
 ow of St John's College. His lab is interested in how movements are contro
 lled by neural circuits. Our everyday movements are performed with little 
 conscious thought and are remarkably precise. Despite what the textbooks t
 ell you\, the neural mechanisms by which this is accomplished are poorly u
 nderstood. We work at several levels\, particularly at the spinal cord and
  cerebellum.\n\nHis work involves electrophysiology\, recording and analys
 ing the signals neurons use to talk to each other. Most current work relat
 es to the cerebellum\, which has a well defined circuitry\, and how it con
 tributes to a learning process that  ‘automates’ movements.\n\n\nRegis
 ter in advance for this meeting:\nhttps://us02web.zoom.us/meeting/register
 /tZIkfu6orTojGNNImfj9cTXs_YllBxA_TVP1 \n\nAfter registering\, you will rec
 eive a confirmation email containing information about joining the meeting
 .
LOCATION:Register on Zoom - link in abstract
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