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SUMMARY:Mass spectrometry: From ribosomes to receptors - Professor Dame Ca
 rol Robinson DBE FRS FMedSci
DTSTART:20210316T180000Z
DTEND:20210316T193000Z
UID:TALK157471@talks.cam.ac.uk
CONTACT:92260
DESCRIPTION:This talk is open to all regardless of membership.\nRegister h
 ere: https://forms.gle/6Y4pZ5Sdqd3iKTaH9\n\nAbstract:\n\nDiscovered in Cam
 bridge in the 1940’s\, mass spectrometry has its origins in the separati
 on of isotopes. Dramatic transformations in the early 1990’s enabled mas
 s spectrometry to be applied to peptides and proteins from electrosprayed 
 bubbles. This approach is now the mainstay of proteomics. Another avenue o
 f research\, much less explored\, was prompted by experimental observation
 s that macromolecular complexes could survive the phase transition\, from 
 solution to the vacuum inside the mass spectrometer. However\, this resear
 ch was not without controversy. How were protein complexes that exist in s
 olution captured in the gas phase? Over the years I have focussed my resea
 rch on this question. From the mass spectra of intact ribosomes to the int
 ricacies of receptor coupling I will show how mass spectrometry has come o
 f age for structural biology.\n\nSpeaker profile:\n\nProfessor Dame Carol 
 Robinson holds the Chair of Dr. Lee’s Professor of Chemistry at the Univ
 ersity of Oxford. Her research focuses on using mass spectrometry to study
  the 3D structure of proteins and their complexes. Prof Robinson completed
  her graduate education while working full-time in industry. She was subse
 quently admitted to the University of Cambridge where she completed her Ph
 D in two years. Following an eight-year career break to begin raising her 
 three children\, she returned to research at Oxford. In 2001\, she became 
 the first female Professor in Chemistry at the University of Cambridge\, r
 eturning to Oxford in 2009 to take up the Chair of Dr. Lee’s Professor o
 f Chemistry. Her research has attracted numerous international awards and 
 prizes\, the most recent ones including: The Royal Medal ‘A’ from the 
 Royal Society\, the Stein & Moore Award from the Protein Society\, the 201
 9 Novozymes Prize from the Novo Nordisk Foundation and the Field & Frankli
 n Award from the American Chemical Society. Prof Robinson was elected as a
  Foreign Associate of the US National Academy of Sciences in 2017 and is a
  past President of the Royal Society of Chemistry. For her contribution to
  science and industry\, Dame Carol was awarded the Dame Commander of the O
 rder of the British Empire (DBE) in the 2013 New Year Honours.
LOCATION:Google Meets
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