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SUMMARY:Physics of blastocyst morphogenesis - Dr. Jean-Léon Maître (Inst
 itut Curie\, Paris) &amp\; Dr. Hervé Turlier (Collège de France\, Paris)
DTSTART:20210505T160000Z
DTEND:20210505T170000Z
UID:TALK158704@talks.cam.ac.uk
CONTACT:Dr. Adrien Hallou
DESCRIPTION:The formation of the blastocyst during preimplantation develop
 ment constitutes a unique opportunity to study living mammalian embryos. T
 he blastocyst consists of a surface epithelium enveloping a fluid-filled l
 umen and a cluster of pluripotent stem cells. This specific architecture i
 s key for the implantation and further the development of the mammalian em
 bryo. Using biophysical measurements and modelling\, we have uncovered ove
 r the past years some of the mechanisms shaping the blastocyst. We will di
 scuss how changes in mechanical properties of cells drive the compaction o
 f the embryo\, differential positioning of cells within the embryo and the
  formation of the first mammalian lumen.
LOCATION:Webinar
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