BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Cell morphogenesis across scales\, from molecules to forces - Prof
 . Ewa Paluch  Department of Physiology\, Development and Neuroscience\, Un
 iversity of Cambridge
DTSTART:20210414T093000Z
DTEND:20210414T103000Z
UID:TALK158905@talks.cam.ac.uk
CONTACT:Akhila Kadgathur Jayaram
DESCRIPTION:A precise control of cell morphology is key for cell physiolog
 y\, and cell shape deregulation is at the heart of many pathological disor
 ders\, including cancer. Cell morphology is intrinsically controlled by me
 chanical forces acting on the cell surface\, to understand shape it is thu
 s essential to investigate the regulation of cellular mechanics.\n\nIn ani
 mal cells\, shape is primarily determined by the cellular cortex\, a thin 
 network of actin filaments and myosin motors underlying the plasma membran
 e. We investigate how the mechanical properties of the cell surface arise 
 from the microscopic organisation of the cortex\, and how changes in these
  properties drive cell deformation. We have developed methods to investiga
 te cortex composition and nanoscale architecture\, and are exploring how c
 ortical network mechanics are regulated. Using a combination of cell biolo
 gy experiments\, quantitative imaging and physical modelling\, we aim to u
 nderstand the control of cell shape across scales.
LOCATION:https://zoom.us/j/92582731025
END:VEVENT
END:VCALENDAR