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SUMMARY:Investigating the immune interactions of liposomes - unravelling d
 irect and indirect effects on complex systems. - Dr Neill Liptrott\, Lectu
 rer in Pharmacology at the University of Liverpool
DTSTART:20210422T150000Z
DTEND:20210422T160000Z
UID:TALK159448@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:Neill’s research investigates the biological interactions of
  conventional and nanotechnology-enabled medicines and therapeutics\; enco
 mpassing assessment of the biocompatibility\, immuomodulatory potential an
 d risk of these novel therapeutic strategies to aid in the preclinical eva
 luation of new materials as well enabling future rational design of nanoma
 terials and therapies.  Neill has worked at the National Institutes of Hea
 lth (NIH) National Cancer Institute’s (NCI) Nanotechnology Characterisat
 ion Laboratory (NCL) based in Frederick\, Maryland\, USA and is a Lecturer
  in the Department of Pharmacology and Therapeutics where he heads a numbe
 r of advanced therapeutics/materials immunocompatibility research programm
 es. Additionally\, Neill is a member of the Core Expert Team (CET) and Ass
 ay Group leader (Immunotoxicity and Haematotoxicity) for the European Nano
 medicine Characterisation Laboratory (EUNCL). Although our work spans many
  different advanced materials and complex medicines\, this talk will detai
 l some of our work on liposomes\, given the recent resurgence due to their
  application in the COVID-19 vaccination programmes. In the context of car
 riers for small molecules and nucleic acids\, we will discuss known intera
 ctions with the immune system that may affect their biocompatibility or re
 veal novel properties that give a therapeutic advantage. In particular\, w
 e will discuss our efforts to link together systems that may interact to b
 ring about unwanted effects.
LOCATION:Meeting ID: 837 8058 8985 Passcode: 428653
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