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SUMMARY:&quot\;Identifying lipid signals in normal and diseased cells&quot
 \; - Prof Michael Wakelam (Babraham Institute Director)
DTSTART:20090311T200000Z
DTEND:20090311T213000Z
UID:TALK16041@talks.cam.ac.uk
CONTACT:Dr Karyn Megy
DESCRIPTION:Lipids are key components of all cellular membranes\, addition
 ally they are an essential part of our diet\, however\, they are not simpl
 y static entities providing cell structure and energy stores. A range of l
 ipids act as intra-and inter-cellular signals controlling cell functions s
 uch as migration\, secretion\, cell proliferation and survival and loss of
  regulation of the generation or removal of signalling lipids occurs in a 
 range of diseases such as cancer and some autoimmune disorders. Not all li
 pid species within a class of lipids acts as a signal\, for instance the o
 ften quoted importance of polyunsaturated versus unsaturated fats in our d
 iets has a biochemical basis in determining whether certain lipids are sig
 nals or stores. Recent advances in mass spectroscopy has allowed analysis 
 leading to a greater understanding of the roles of these lipid signals and
  points to novel therapeutic targets and the possibility of lipids as biom
 arkers.
LOCATION:Pharmacology Lecture Theatre\, Department of Pharmacology\, Tenni
 s Court Road
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