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SUMMARY:Meta-analytic evidence of differential prefrontal and early sensor
 y cortex activity during non-social sensory perception in autism - Nazia J
 assim\, Department of Psychiatry
DTSTART:20210519T150000Z
DTEND:20210519T160000Z
UID:TALK160603@talks.cam.ac.uk
CONTACT:Katharina Zuhlsdorff
DESCRIPTION:To date\, neuroimaging research has had a limited focus on non
 -social features of autism. As a result\, neurobiological explanations for
  atypical sensory perception in autism are lacking. To address this\, we q
 uantitively condensed findings from the non-social autism fMRI literature 
 in line with the current best practices for neuroimaging meta-analyses. Us
 ing activation likelihood estimation (ALE)\, we conducted a series of robu
 st meta-analyses across 83 experiments from 52 fMRI studies investigating 
 differences between autistic (n = 891) and typical (n = 967) participants.
  We found that typical controls\, compared to autistic people\, show great
 er activity in the prefrontal cortex (BA9\, BA10) during perception tasks.
  More refined analyses revealed that\, when compared to typical controls\,
  autistic people show greater recruitment of the extrastriate V2 cortex (B
 A18) during visual processing. Taken together\, these findings contribute 
 to our understanding of current theories of autistic perception\, and high
 light some of the challenges of cognitive neuroscience research in autism.
LOCATION:Zoom
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