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SUMMARY:Coping with Mechanical Stress: Tissue dynamics in development and 
 repair - Dr Yanlan Mao\, MRC Laboratory for Molecular Cell Biology\, Unive
 rsity College London
DTSTART:20211014T123000Z
DTEND:20211014T133000Z
UID:TALK161095@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:During growth and development\, tissue dynamics\, such as tiss
 ue folding\, cell intercalations and oriented cell divisions\, are critica
 l for shaping tissues and organs. However\, less is known about how tissue
 s regulate their dynamics during tissue homeostasis and repair\, to mainta
 in their shape after development. In this talk\, we will discuss how diffe
 rential growth rates can generate precise folds in tissues. We will also d
 iscuss how tissues respond to mechanical perturbations\, such as stretchin
 g or wounding\, by altering their actomyosin contractile structures\, to c
 hange tissue dynamics\, and thus preserve tissue shape and patterning. We 
 combine genetics\, biophysics and computational modelling to study these p
 rocesses.
LOCATION:Zoom meeting
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