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SUMMARY:Evolution and development of vertebral regionalization in fishes -
  Katharine Criswell\, Research Associate\, Department of Zoology
DTSTART:20211007T120000Z
DTEND:20211007T130000Z
UID:TALK161857@talks.cam.ac.uk
CONTACT:Anna Belcher
DESCRIPTION:The backbones of land vertebrates (tetrapods) are subdivided i
 nto up to five distinct regions (cervical\, thoracic\, lumbar\, sacral and
  caudal)\, with vertebrae that are different from one another in shape and
  are patterned by the expression of Hox genes in early embryos. Conversely
 \, the backbones of fishes are thought to have fewer regions\, consisting 
 of just a trunk and tail\, and the relationship of Hox genes to vertebrae 
 in fishes is unclear. To understand how backbone shape has evolved across 
 fishes and how Hox genes might have patterned vertebrae outside of tetrapo
 ds\, I used quantitative methods to compare vertebrae along the body and s
 tudied Hox gene expression in a cartilaginous fish\, the little skate. I f
 ound that fish have more vertebral regions than previously appreciated\, a
 nd that Hox genes were likely responsible for developing these regions in 
 the earliest jawed vertebrates.
LOCATION:King Richard Room\, Darwin College
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