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SUMMARY:Morphogenesis and cell ordering in bacterial biofilms  - Jing Yan
DTSTART:20211018T133000Z
DTEND:20211018T143000Z
UID:TALK162505@talks.cam.ac.uk
CONTACT:Dr. Wolfram Pönisch
DESCRIPTION:Biofilms\, surface‐attached communities of bacterial cells\,
  are a concern in health and in industrial operations because of persisten
 t infections\, clogging of flows\, and surface fouling. In this talk\, I w
 ill discuss about our recent progress in using Vibrio cholerae as a model 
 biofilm former to reveal the mechanical principles behind biofilm formatio
 n\, both at the single cell level and at the continuum level. I will first
  present a new methodology to image living\, growing bacterial biofilms at
  single-cell resolution\, and demonstrate how cell-to-surface adhesion and
  growth-induced flow together drive a collective cell reorientation cascad
 e in V. cholerae biofilms. Next\, I will demonstrate how external confinem
 ent profoundly changes the morphogenesis pathway and cellular organization
  inside a biofilm. Finally\, I will delve into the molecular mechanisms un
 derlying V. cholerae adhesion and biofilm development.
LOCATION:Online
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