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SUMMARY:Developmental Control of Avian Skin Patterning - Marie Manceau
DTSTART:20211206T143000Z
DTEND:20211206T153000Z
UID:TALK162511@talks.cam.ac.uk
CONTACT:margherita battistara
DESCRIPTION:During pattern formation\, morphogenetic events provide a resp
 onse of the naïve tissue to chemical and mechanical positional cues. To w
 hat extent these processes shape pattern establishment and contribute to n
 atural variation remains unclear. We studied cell dynamics occurring durin
 g the emergence of feather array geometries in birds\, which involves a gr
 adual regionalisation of the skin through self-organisation. We identified
  highly dynamic modifications of local cell density\, movement\, and shape
  occurring during primordia emergence in the Japanese quail. Using inter-s
 pecies comparison in poultry\, finch\, emu\, ostrich and penguin embryos\,
  followed by perturbation of skin architecture ex vivo\, we showed that or
 iented anisotropy of dermal cells prior to primordia formation is necessar
 y for the regularity of the final array. Our results provide key insights 
 into the cellular basis of self-organisation and demonstrate that initial 
 tissue morphology constrains pattern attributes\, uncovering a morphogenet
 ic mechanism contributing to pattern evolution.
LOCATION:Online
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