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SUMMARY:Measuring and Modeling the coordination of cilia: from collective 
 waves in the brain to information processing? - Pietro Cicuta\, Department
  of Physics\, University of Cambridge
DTSTART:20211112T160000Z
DTEND:20211112T170000Z
UID:TALK162688@talks.cam.ac.uk
CONTACT:Prof. Jerome Neufeld
DESCRIPTION:In the last decade we have investigated the emergence of synch
 ronised collective states in the dynamics of two or more motile cilia. Mot
 ile cilia are filaments of around 10 microns in length\, they beat by the 
 coordinated action of molecular motors along the filament. In systems of s
 everal cilia\, the beat across cilia can become phase locked\, leading to 
 fluid transport or propulsion.\nWe have pushed two directions in my team: 
 (1) experiments on lung and brain tissue models\, and (2) models that redu
 ce the complexity of each cilium to the extreme\, to enable attempts at de
 scribing the collective motion.\nFor such a specific organelle (although p
 resent in a wide range of eukaryotic cells) the range of physics and pheno
 mena that arise are really diverse.  The ciliary collective motions I will
  show are at play in mammalian embryonic development\, in the lungs and br
 ains\, but can also carry information directionally and be used to form lo
 gical circuits in a form of physical computation.  In this talk we will re
 view recent progress and some unpublished results.
LOCATION:MR2\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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