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SUMMARY:Mitochondria: portrait of an inflammatory killer - Professor Steph
 en Tait | Beatson Institute
DTSTART:20220622T140000Z
DTEND:20220622T150000Z
UID:TALK165361@talks.cam.ac.uk
CONTACT:Hannah Burns
DESCRIPTION:Mitochondria play an essential role in apoptotic cell death. T
 he textbook view of apoptosis is as a silent form of cell death\; this mak
 es intuitive sense given the billions of cells that die each day through a
 poptosis. Nonetheless\, recent work from us and others has shown that alon
 gside triggering cell death\, mitochondria elicit inflammation. Some of th
 ese inflammatory pathways likely stem from the bacterial ancestry of mitoc
 hondria. I will discuss how mitochondria can engage cell-death associated 
 inflammation and how we can therapeutically harness these processes to imp
 rove cancer treatment. Finally\, I will discuss our recent efforts to unde
 rstand “day jobs” of cell-death associated inflammation\, specifically
  in the context of senescence and aging.
LOCATION:Online (Zoom) - contact organiser for details
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