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SUMMARY:Multicellular synthetic biology: Understanding the design principl
 es of intercellular communication - Professor Matthew R. Bennett\, Rice Un
 iversity
DTSTART:20211213T180000Z
DTEND:20211213T190000Z
UID:TALK166924@talks.cam.ac.uk
CONTACT:Georgeos Hardo
DESCRIPTION:Biologists have long sought to rationally engineer genetic reg
 ulatory networks for a variety of reasons. For instance\, the basic scienc
 e of understanding gene regulation has prospered due to our ability to int
 ricately construct\, perturb\, and monitor gene networks in living cells. 
 Further\, synthetic biologists have designed a host of systems for practic
 al biomedical and industrial applications. However\, as synthetic biology 
 pushes the limits of genetic engineering it is becoming increasing clear t
 hat synthetic multicellular systems will be required to accomplish tasks t
 hat are difficult for single cells or homogeneous colonies. In this talk\,
  I will describe our lab’s recent efforts to better understand and engin
 eer intercellular communication in multicellular bacterial systems. In par
 ticular\, I will discuss how the network topologies of intercellular gene 
 regulatory networks influence the spatiotemporal coordination of gene expr
 ession in synthetic microbial consortia. Further\, I will present recent e
 ngineering work in which we designed and implemented a system that allows 
 E. coli to asymmetrically and irreversibly differentiate into multiple cel
 l types. Overall\, our results point the way toward engineering synthetic 
 “organisms” from the ground up.\n\nTo register for the talk\, follow t
 his link https://bit.ly/CUSBS_M21_key
LOCATION:To register for the talk\, follow this link https://bit.ly/CUSBS_
 M21_key
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