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SUMMARY:Causality\, Perturbations\, Gene Regulation\, and Drug Repurposing
  - Caroline Uhler\, Co-Director of the Eric and Wendy Schmidt Center at th
 e Broad Institute of MIT and Harvard
DTSTART:20220328T130000Z
DTEND:20220328T140000Z
UID:TALK166999@talks.cam.ac.uk
CONTACT:105893
DESCRIPTION:An exciting opportunity at the intersection of single-cell bio
 logy and machine learning stems from the growing availability of large-sca
 le perturbational data (drugs\, knockouts\, overexpression\, etc.). I will
  present a framework based on causality and autoencoders that can integrat
 e observational and perturbational data and discuss applications to learni
 ng gene regulatory networks as well as predicting the effect of new pertur
 bations. We end by discussing how such a framework can be applied for drug
  repurposing in the current COVID-19 crisis.\n\nhttps://zoom.us/j/94724443
 844?pwd=c1VyTHlkZWF2OCsxUG5oWGlROHJqdz09\n
LOCATION:Zoom
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