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SUMMARY:Colour within the lines – a personal perspective of navigating a
 cademia as a black woman - Dr Ane Ogbe\; Postdoctoral Scientist\, Universi
 ty of Oxford
DTSTART:20220202T133000Z
DTEND:20220202T143000Z
UID:TALK167071@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:My research interest is focused on gaining deeper insights int
 o the dynamic role of CD4 and CD8+ T cells in the development and maintena
 nce of immunity to infectious diseases. \n\nFor my Ph.D. studies at Brunel
  University\, London\, I investigated the role of 2 immunoregulatory genes
   - Egr2 and 3 -  in regulating the immune response. We identified a novel
  role of these genes as key players in regulating CD4+ Tfh cell differenti
 ation. For my post-doctoral work at the University of Oxford\, I have focu
 sed more on human immunology where I investigated the role of T cells part
 icularly CD4+ Tfh cells as one of the key cellular drivers of antibody res
 ponse leading to the induction of broadly neutralising antibodies (bNAbs) 
 in HIV infection. I proceeded to work on the RIO (Rockefellar\, Imperial a
 nd Oxford Collaboration) HIV clinical trial\, a randomised\, double-blind\
 , placebo-controlled clinical trial\, where long-acting dual bNAbs are adm
 inistered to HIV+ volunteers followed by treatment interruption with time 
 to viral rebound as the primary endpoint. Faced with the pandemic\, I have
  used my knowledge and skillsets in HIV immunology to work on characterisi
 ng the immunology induced by SARS-COV-2 in natural infection and vaccinati
 on settings across immunocompetent and immunosuppressed cohorts\, addressi
 ng pertinent questions regarding magnitude\, durability and quality of the
  immune response. The insights gained from my work on HIV and SARS-COV-2 i
 mmunology is crucial in informing the development of therapeutic modalitie
 s including vaccine strategies useful for the rational design of prophylac
 tic and therapeutic vaccines.\n\nClick here to join live - https://us06web
 .zoom.us/j/87289606090 
LOCATION:Online via zoom
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