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SUMMARY:Effect of nutrients on microglial function - Agnès Nadjar\, Unive
 rsity of Bordeaux\, France
DTSTART:20220207T160000Z
DTEND:20220207T170000Z
UID:TALK168590@talks.cam.ac.uk
CONTACT:47293
DESCRIPTION:Microglia are the brain macrophages\, eliciting multifaceted f
 unctions to maintain brain homeostasis across lifetime and in all pathophy
 siological conditions. A new line of research suggests that metabolic plas
 ticity plays a crucial role in regulating microglial function. Hence\, the
  nature of nutrients reaching the brain to feed microglia could control it
 s immunosurveillance ability to maintain homeostasis within the brain. Whi
 le\, brain energy metabolism and substrate availability vary under physiol
 ogy and disease states\, how these variations influence microglial functio
 n and eventually affect neuronal control of behavior and physiology is rel
 atively unknown.\nIn this talk\, I will detail part of our work on the mec
 hanisms regulating microglial metabolism and the consequences on its activ
 ity\, when the fueling of the brain has changed\, during neurodevelopment 
 or under obesity.
LOCATION:https://zoom.us/j/95266584173?pwd=Q3pDZDJ3NVMzdmdnbit4cEtwV2ZOUT0
 9  Meeting ID: 952 6658 4173 Passcode: anjuAgjXX3
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