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SUMMARY:Characterization of a Mechanical Hotspot for Cell Plate Guidance N
 ear an Adjacent Three-Way Junction  - Marie-Cécile Caillaud\, CR CNRS
DTSTART:20220124T143000Z
DTEND:20220124T153000Z
UID:TALK168962@talks.cam.ac.uk
CONTACT:Dr. Wolfram Pönisch
DESCRIPTION:When it comes to building an organ\, cells need to coordinate 
 with each other to form a functional tissue layer. In epithelia\, cells at
 tach to each other forming at their edges. In animals\, mechanical stresse
 s and mechano-sensitive signaling pathways play a central role in the form
 ation and maintenance of three-way junctions (3WJ)\, which are topological
 ly stable structures. In walled multicellular organisms\, like land plants
 \, the coordination of the 3WJ formation during cell division\, and the co
 rresponding avoidance of 4WJ\, remains poorly understood and is often pict
 ured as a passive consequence of cell division. Here\, we report the exist
 ence of two positions at a conserved distance\, above and below an existin
 g 3WJ where cell plate insertion could occur in the Arabidopsis root corte
 x. This phenomenon\, observed in other plants\, is under genetic control: 
 In an Arabidopsis mutant sac9-3\, the cell plate abnormally attaches at tw
 o equidistant positions from an adjacent 3WJ\, both in the root and shoot.
  The number of ill-formed junctions in sac9-3 mutant increased with the in
 tensity of turgor-induced stresses borne by cell walls. This confirms our 
 initial hint that stress plays a role in cell junction formation. Moreover
 \, the sac9-3 mutants feature an impaired metabolism of the PI(4\,5)P2 pho
 spholipid suggesting that lipid within the plasma membrane could play a ro
 le in the mechano-transduction pathway guiding cell plate attachment. 
LOCATION:Online
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