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SUMMARY:Insights into emotional processing from intracranial recordings an
 d their potential for biomarker discovery in affective disorders - Dr Saur
 abh Sonkusare\, University of Cambridge
DTSTART:20220210T123000Z
DTEND:20220210T133000Z
UID:TALK169124@talks.cam.ac.uk
CONTACT:87079
DESCRIPTION:*Abstract:* Intracranial recordings provide the distinct advan
 tage of direct high fidelity signals at neuronal population level providin
 g the means to uncover the precise frequency dependent activity and coupli
 ng among brain regions. Such knowledge is of significant value in the evol
 ving field of neuromodulation (at node/network level) to understand the ne
 urobiological basis of emotional processing and its dysfunction. In this t
 alk I will first show how intracranial recordings from the amygdala\, orbi
 tofrontal cortex and medial prefrontal cortex allow investigation of emoti
 onal valence differentiation and the connectivity profile. Furthermore\, t
 o highlight the translational potential of such intracranial recordings\, 
 I will present results from a study of habenular recordings investigating 
 valence differentiation and non-oscillatory component of the power spectru
 m which can be used to characterise the severity of depression.\n\n*Biogra
 phy:* Dr Saurabh Sonkusare completed his PhD in QIMR Berghofer/ The Univer
 sity of Queensland\, Australia\, in 2019 under Prof Michael Breakspear. In
  2020\, he joined the Department of Psychiatry\, University of Cambridge\,
  as a post-doc in Prof Valerie Voon’s research group. Dr Sonkusare utili
 ses neuroimaging (LFPs\, fMRI) and neuromodulation tools (TMS) to understa
 nd the functioning of key brain regions\, their interactions as well as me
 so/macroscale brain dynamics. He also specialises in psychophysiological m
 easures (heart rate and skin conductance) and especially facial thermal im
 aging having developed methods for its analyses. Together these two stream
 s of research form the basis for his investigations on emotions\, brain-bo
 dy communication and their dysfunction in affect\, anxiety and addiction d
 isorders. \n
LOCATION:Zoom (Please contact mho28@medschl.cam.ac.uk)
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