BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Contacts govern the adaptive mechanics of branched actin networks 
 - Mehdi Bouzid\, CNRS Univ. Grenoble Alpes
DTSTART:20220308T130000Z
DTEND:20220308T140000Z
UID:TALK169802@talks.cam.ac.uk
CONTACT:Camille Scalliet
DESCRIPTION:Gels of fibrous biopolymers are ubiquitous within cells and th
 eir rigidity is crucial for their function [1]. Our current understanding 
 of their elastic response is usually understood as an interplay between th
 e bending and stretching of their filaments [2]. This point of view howeve
 r fails when applied to the weakly coordinated branched actin networks fou
 nd throughout the cell [3\, 4]. Through experiments and theory\, we show t
 hat transient contacts between entangled filaments govern their adaptive m
 echanics. Additional contacts may get locked in during network growth\, se
 tting the final properties of the system [5]. These properties could be ke
 y to understanding how moving cells dynamically adapt their cytoskeleton t
 o their environment.\n\n[1] G Letort\, H Ennomani\, L Gressin\, M Thery\, 
 and L Blanchoin. Dynamic reorganization of the actin cytoskeleton. F1000Re
 search\, 4\, 2015.\n\n[2] C. P Broedersz\, X Mao\, T C Lubensky\, and F. C
  MacKintosh. Criticality and isostaticity in fibre networks. Nature Physic
 s\, 7(12):983\, 2011.\n\n[3] P Bauer\, J Tavacoli\, T Pujol\, J Planade\, 
 J Heuvingh\, and O Du Roure. A new method to measure mechanics and dynamic
  assembly of branched actin networks. Scientific reports\, 7(1):15688\, 20
 17.\n\n[4] A Allard\, M Bouzid\, T Betz\, C Simon\, M Abou-Ghali\, J Lemie
 re\, F Valentino\, J Manzi\, F Brochard-Wyart\, K Guevorkian\, et al. Acti
 n modulates shape and mechanics of tubular membranes. Science advances\, 6
 (17):eaaz3050\, 2020.\n\n[5] M Bouzid\, C Valencia Gallardo\, L Koehler\, 
 G Foffi\, J Heuvingh\, O du Roure\, and M Lenz. Elasticity from entangleme
 nts in branched actin. In preparation.\n
LOCATION:Center for Mathematical Sciences\, Lecture room MR11\, or https:/
 /maths-cam-ac-uk.zoom.us/j/98016675669
END:VEVENT
END:VCALENDAR