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SUMMARY:Computational Neuroscience Journal Club - Jake Stroud and Michal W
 ojcik
DTSTART:20220208T133000Z
DTEND:20220208T150000Z
UID:TALK169850@talks.cam.ac.uk
CONTACT:Jake Stroud
DESCRIPTION:Please join us for our fortnightly journal club online via zoo
 m where two presenters will jointly present a topic together. The next top
 ic is ‘Structured vs random mixed selectivity in frontal cortex’ prese
 nted by Jake Stroud and Michal Wojcik.\n\nZoom information: https://us02we
 b.zoom.us/j/84958321096?pwd=dFpsYnpJYWVNeHlJbEFKbW1OTzFiQT09 Meeting ID: 8
 49 5832 1096 Passcode: 506576\n\nSummary:\nHistorically\, neuroscientists 
 have focused on analysing what single neurons represent (ie what a neuron 
 is selective to). This has been a fruitful approach for understanding seve
 ral brain areas (such primary visual cortex)\, however\, more recent studi
 es suggest that this approach may not apply so readily to frontal cortices
 . This is mainly because neurons in frontal cortex have been shown to be s
 elective to multiple task features (they display mixed selectivity). Theor
 etical studies suggest that if neurons display random mixed selectivity\, 
 this allows a brain area to perform many complex tasks. Following this\, e
 mpirical studies have found evidence of such random mixed selectivity in f
 rontal cortex\, however several recent papers (both theoretical and empiri
 cal) suggest the opposite: that non-random (ie more classical structured) 
 selectivity is actually expected for certain tasks. In this journal club w
 e will review these studies and we’ll offer some theoretical justificati
 on as to why some studies find evidence for random mixed selectivity and w
 hy others find evidence for structured selectivity.\n\nKey papers:\n\nThe 
 importance of mixed selectivity in complex cognitive tasks\, Rigotti et al
 .\, Nature\, 2013\, https://www.nature.com/articles/nature12160\n\nA categ
 ory-free neural population supports evolving demands during decision-makin
 g\, Raposo et al.\, Nature Neurosi.\, 2014\, https://www.nature.com/articl
 es/nn.3865\n\nFrontal cortex neuron types categorically encode single deci
 sion variables\, Hirokawa et al.\, Nature\, 2019\, https://www.nature.com/
 articles/s41586-019-1816-9\n\nThe role of population structure in computat
 ions through neural dynamics\, Dubreuil et al.\, bioRxiv\, 2021\, https://
 www.biorxiv.org/content/10.1101/2020.07.03.185942v2.full
LOCATION:Online on Zoom
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