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SUMMARY:HPV vaccines – a success story from the bench to the clinic - Pr
 ofessor Margaret Stanley\, Department of Pathology
DTSTART:20090401T152000Z
DTEND:20090401T154500Z
UID:TALK17131@talks.cam.ac.uk
CONTACT:Gigi Moller
DESCRIPTION:Viral infections cause at least 15% of all cancers\; one of th
 e most important oncogenic viruses is the human papillomavirus (HPV) a cau
 sal agent in 4% of all cancers.  The identification of the major oncogenic
  HPV’s HPV 16 and HPV 18 by Harald zur Hausen was recognised in 2008 by 
 the award to him of the Nobel Prize in Medicine.  The unfolding of the HPV
  story started in the 1970’s and has resulted in the development of prop
 hylactic vaccines using sophisticated recombinant molecular techniques and
  protein expression to prevent infection by HPV 16 and 18.  These vaccines
  are now licensed world wide and have been incorporated into national immu
 nisation programmes in several countries The vaccines are remarkably effic
 acious\, generate strong immunity and have a very good safety profile and 
 over the medium to long term should reduce the incidence of cervix cancer 
 and other HPV associated cancers significantly
LOCATION:Centre for Mathematical Sciences\, Meeting Room 2
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