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SUMMARY:Cybergenetics: A control theory for living cells - Corentin Briat\
 , ETH-Zürich
DTSTART:20220331T130000Z
DTEND:20220331T140000Z
UID:TALK172106@talks.cam.ac.uk
CONTACT:Xiaodong Cheng
DESCRIPTION:The objective of this talk is to give an idea of the problems 
 encountered in the control of biological systems\, and how they can be sol
 ved. In particular\, we will discuss the concept of reaction networks as m
 odels for a wide class of dynamical systems including biological\, ecologi
 cal\, and epidemiological systems. The concept of noise or randomness an i
 ts role in those systems will be also discussed. When starting the discuss
 ion on the control of biological processes\, a parallel between the concep
 t of regulation\, integral action\, homeostasis and perfect adaptation wil
 l be drawn and will serve as a bridge between control theory and biology. 
 Various control paradigms will be briefly introduced\, with a specific emp
 hasis on the in-vivo control of cellular networks\, that is the design of 
 controllers that can be implemented inside living organisms\, such as bact
 eria. A solution to the robust regulation problem based on the so-called A
 ntithetic Integral Controller will also be discussed and shown to theoreti
 cally work both in the deterministic and the stochastic settings. Finally\
 , the approach discussed in the talk will be illustrated via simulations a
 nd experimental results.
LOCATION:Baker Building - Board Room\, Department of Engineering / Online 
 (Zoom Meeting ID: 856 3342 6333 Passcode: 367773)
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