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SUMMARY:The Timescale Dynamics of Epilepsies: From Seconds to Decades - Ch
 ristophe Bernard\, Institute of Systems Neuroscience\, Inserm\, France
DTSTART:20220331T100000Z
DTEND:20220331T110000Z
UID:TALK172112@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:Continuous long-term recordings (months to years) in patients 
 with epilepsy directly show that seizures are regulated in a circadian man
 ner in 80% of the cases. Besides\, these recordings allowed to prove the p
 resence of a much slower rhythm (days to weeks) of seizures. They strongly
  suggest the existence of specific molecular processes that influence the 
 time of occurrence of seizures. I will show that cortical structures under
 go dynamic reconfiguration of their molecular architecture in a daily mann
 er in health and disease. Accounting for daily and multidien molecular rhy
 thms is essential to our understanding of brain function and dysfunction. 
LOCATION:Electrical Engineering\, Department of Engineering - CGC Seminar 
 Room\, 9 JJ Thomson Avenue\, Cambridge\, CB3 0FA
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