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SUMMARY:Size-dependence of switching and stable behavior in biochemical sy
 stems  - Monika Jozsa\, University of Cambridge
DTSTART:20220526T130000Z
DTEND:20220526T140000Z
UID:TALK174950@talks.cam.ac.uk
CONTACT:Xiaodong Cheng
DESCRIPTION:Biochemical reactions occur in cellular compartments with vary
 ing volumes where the number of molecules can have a large range. This rai
 ses the question of how such systems can operate reliably throughout this 
 range. In particular\, it is not well understood how small systems\, where
  the randomness of reactions dominates and any change in the number of mol
 ecules has a larger effect\, can reliably control their volume.\n\nIn this
  talk\, I will introduce a conceptual biochemical system that controls its
  own size in response to external input. This system describes the time ev
 olution of two mutually inhibitory species. It acts like a switch when it 
 is small\, realizing growth and shrinkage\, and gradually becomes stable a
 s it gets larger\, preventing excessive growth. I will discuss why such a 
 system may arise and be functionally and strategically beneficial for biol
 ogical systems. I will also talk about other systems with multiple species
  and mixed connections (inhibitory and excitatory) that have similar behav
 iours.\n
LOCATION:Dyson Teaching Room\, Department of Engineering / Online (Zoom)
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