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SUMMARY:Neural and Vascular Biomarkers for Non-invasive Bedside Assessment
  of Cerebral Autoregulatory Health. - Deepshikha Acharya Carnegie Mellon U
 niversity 
DTSTART:20220608T111500Z
DTEND:20220608T121500Z
UID:TALK175310@talks.cam.ac.uk
CONTACT:Kirsty Shepherd
DESCRIPTION:Timely diagnosis and management of the cerebral autoregulatory
  state in neurocritical patients can greatly improve patient prognosis. Wh
 ile in a healthy brain local neural activity and hemodynamics are well mat
 ched\, a disruption of cerebral autoregulation can drastically alter cereb
 ral blood flow\, affecting neuronal function and associated cerebral metab
 olism. Using bedside non-invasive neuroimaging techniques such as diffuse 
 optical spectroscopy and electroencephalogram\, we study the changes in ne
 uro-vascular synergy with autoregulatory state in controlled preclinical m
 odels. Here\, we propose three different neuro-vascular mechanisms that al
 ter with cerebral dysregulation and can act as biomarkers for clinical ass
 essment of cerebral health. 
LOCATION:Electrical Engineering\, Department of Engineering - CGC Seminar 
 Room\, 9 JJ Thomson Avenue\, Cambridge\, CB3 0FA
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