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SUMMARY:Mycobacterium tuberculosis genome economization for pathogenesis: 
 “More from less for more” - Prof Seyed E. Hasnain\, Indian Institute o
 f Technology\, Delhi and Sharda University\, Greater Noida 
DTSTART:20220707T150000Z
DTEND:20220707T160000Z
UID:TALK176363@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Abstract: Mycobacterium tuberculosis (M.tb) is the deadliest b
 acterial pathogen known to humanity causing the disease TB\, taking the la
 rgest toll of human lives globally with a person dying every 15-20 seconds
  despite the fact that TB is completely curable if diagnosed timely and tr
 eated properly. This problem is further compounded by the development of d
 rug resistance\, to the extent of total drug resistance\, HIV AIDS co-infe
 ction and the accompanying TB-IRIS and the impending impact of the emergin
 g diabetes epidemic and of late the COVID-19 pandemic. M.tb has undergone 
 reductive evolution\, over millions of years\, into a very slim and trim g
 enomic and functional architecture. Not only has it shed much of its genom
 e\, but has balanced this genome deficit by resorting to very intelligent 
 survival strategies such as gene co option\, moon lighting and molecular m
 imicry. \n\n
LOCATION:Venue to be confirmed
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