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SUMMARY:Early Life Microbiomes and Long-Term Health - Dr Trevor Lawley fro
 m Wellcome Sanger Institute\, Hinxton\, Cambridgeshire
DTSTART:20230309T130000Z
DTEND:20230309T140000Z
UID:TALK177803@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:Humans are born without microbiota but are rapidly colonised b
 y microbes from our mothers and the surrounding environment at birth. The 
 dynamic processes of gut microbiota colonisation and assembly are poorly u
 nderstood\, but possibly represent a deeply evolved ecological succession 
 analogous to an infant's organ and system developmental programmes. Import
 antly\, clinical procedures (C-section\, antibiotics) that perturb microbi
 ota acquisition and assembly are associated with a higher rate of infectio
 n\, autoimmunity\, metabolic syndromes in early childhood. Therefore\, the
  stereotypic assembly trajectory of the microbiota is believed to drive ch
 ildren's immune development and growth. This seminar will discuss the UK B
 aby Biome Study aimed to map microbiota assembly in infants to identify as
 sociations between the stages of microbiota assembly and landmarks in a ch
 ild’s growth and development\, and to inform the discovery of microbiota
 -focused interventions to optimise a child’s growth\, development and di
 sease resistance.
LOCATION:Biffen Lecture theatre and Zoom
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