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SUMMARY:Environment-neuroendocrine interactions regulating larval settleme
 nt in the marine worm Platynereis - Elizabeth Williams\, University of Exe
 ter
DTSTART:20221011T120000Z
DTEND:20221011T130000Z
UID:TALK178646@talks.cam.ac.uk
CONTACT:Stephen Pates
DESCRIPTION:For many marine invertebrates\, larval settlement is a key dev
 elopmental transition. This process is strongly linked to the environment 
 in that larvae must detect specific cues to determine the time and place o
 f settlement. How environmental cues are detected and activate internal ho
 rmone signalling to regulate larval settlement is not yet clear. To better
  understand this\, we are investigating larval settlement in the nereid po
 lychaete Platynereis dumerilii. Behavioural assays show that Platynereis l
 arvae have a species-specific response to biofilms composed of benthic mic
 roalgal diatoms. Platynereis larval settlement is internally regulated by 
 the neuropeptide myoinhibitory peptide (MIP)\, an ortholog of insect allat
 ostatin B neuropeptide. I will discuss recent advances in understanding th
 e function and signalling mechanisms of MIP and assessing its link to envi
 ronmental cue detection in Platynereis. Understanding how external and int
 ernal signals combine to guide the developmental transition of marine inve
 rtebrate settlement will inform our understanding of animal-microalgae int
 eractions and the evolution of environmentally-guided animal development.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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