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SUMMARY:About charge effects and depletion zones: Interactions of proteins
  in  solution and with interfaces - F. Schreiber\, Applied Physics\, Unive
 rsity of Tuebingen
DTSTART:20090430T103000Z
DTEND:20090430T113000Z
UID:TALK18216@talks.cam.ac.uk
CONTACT:Catherine Pearson
DESCRIPTION:After a brief overview of the multiple and competing interacti
 ons in  soft matter\, and a short introduction to how information on the  
 interactions and the resulting correlations can be obtained from  elastic 
 and inelastic X-ray and neutron scattering experiments  (complemented by i
 n-situ (under water) IR and UV/vis spectroscopy)\, we  will discuss select
 ed aspects of protein interactions.\n\nThese include the effect of ionic s
 trength on the effective   interaction potential in dense aqueous solution
 s (transition from  screened Coulombic to effective hard sphere\; F. Zhang
  et al.\, J. Phys.  Chem. B 111 (2007) 251)\, efforts to "locate" the ioni
 c cloud around  proteins and near surfaces\, and experiments to determine 
 the  microscopic and macroscopic dynamics of protein solutions while  unde
 rgoing the denaturing transition. Particular attention will be  given to t
 he recent discovery of  "reentrant condensation" in proteins  (F. Zhang et
  al.\, Phys. Rev. Lett. 101 (2008) 148101).\n\nWe will also discuss our ef
 forts to determine the protein solution   density profile near a solid wal
 l functionalised by a self-assembled  monolayer and the interaction of dif
 ferent functionalities with water  (M. Skoda et al.\, Langmuir 23 (2007) 9
 70\; M. Skoda et al.\, Langmuir\,  (2009)).
LOCATION:Open Plan Area\, BP Institute\, Madingley Rise CB3 0EZ
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