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SUMMARY:Characterisation of structural variation in 24 breast cancer genom
 es using paired-end sequencing on the Illumina Genome Analyser - Phil Stev
 ens\, Wellcome Trust Sanger Institute
DTSTART:20090527T140000Z
DTEND:20090527T150000Z
UID:TALK18361@talks.cam.ac.uk
CONTACT:Katrien Van Look
DESCRIPTION:We have used massively parallel paired end sequencing on the I
 llumina G A to reconstruct the genomic landscape of 24 breast cancer genom
 es\, through the identification and characterization of ~2200 cancer-speci
 fic structural rearrangements. These studies have revealed considerable co
 mplexity in the patterns of structural variation\, identified 19 novel\, e
 xpressed in-frame gene fusions and unveiled new insights into the\ncomplex
  structure of amplicons.\n
LOCATION:Cancer Research UK Cambridge Research Institute\, Room 215
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