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SUMMARY:Microglia in health and disease - Prof. Helmut Kettenmann. Charit
 é Berlin\, Germany
DTSTART:20230206T160000Z
DTEND:20230206T170000Z
UID:TALK183725@talks.cam.ac.uk
CONTACT:Timothy Birkle
DESCRIPTION:We have recently generated a new mouse line which allows us to
  record calcium activity in microglial cells in slices and in vivo. We hav
 e used this mouse line to test whether neuronal activity elicits calcium s
 ignals in microglial cells. We found that Schaffer collateral activation i
 n the hippocampus elicits calcium signals in microglia which are mediated 
 by astrocyte activity. In the second part I will focus on the interaction 
 of microglial cells/ brain macrophages with glioma cells. We found that th
 ese cells acquire a very specific phenotype and there are several mechanis
 ms by which they promote glioma progression.\n
LOCATION:https://zoom.us/j/94128601767?pwd=UklLN2h5ZGNVL3BMYVNqdXh3djRXZz0
 9
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