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SUMMARY:Chromatin:  How a cell fits 10\,000 miles of spaghetti into a bask
 etball - Sam Rowbotham\, The Babraham Institute
DTSTART:20090528T120000Z
DTEND:20090528T124500Z
UID:TALK18469@talks.cam.ac.uk
CONTACT:Dr James Kirkbride
DESCRIPTION:If linearised\, the amount of DNA in a human cell would stretc
 h 2m\, yet this must be contained in a space 6-thousandths of a millimeter
  in diameter\, equivalent to stuffing 10\,000 miles of spaghetti into a ba
 sket ball without any of it tangling or breaking. Amazingly\, the structur
 e that allows this compaction called chromatin is also able to influence w
 hether genes are switched on or off\, how often a cell divides\, and how n
 ew cells can 'remember' exactly what and when they are supposed to do. Thi
 s talk will explore the what's and when's of this remarkable complex.
LOCATION:Entertaining Room\, Darwin College
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