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SUMMARY:Crystallinity characterization of white matter in the human brain 
 - Prof. Erin Teich\, Department of Physics\, Wellesley College\, USA
DTSTART:20221024T130000Z
DTEND:20221024T133000Z
UID:TALK184892@talks.cam.ac.uk
CONTACT:Dr Venkat Kapil
DESCRIPTION:White matter microstructure underpins cognition and function i
 n the human brain through the facilitation of neuronal communication\, and
  the non-invasive characterization of this structure remains an elusive go
 al in the neuroscience community. Efforts to assess white matter microstru
 cture are hampered by the sheer amount of information needed for character
 ization. Current techniques address this problem by representing white mat
 ter features with single scalars that are often not easy to interpret. Her
 e\, we address these issues by introducing tools from soft matterfor the c
 haracterization of white matter microstructure. We investigate structure o
 n a mesoscopic scale by analyzing its homogeneity and determining which re
 gions of the brain are structurally homogeneous\, or ``crystalline" in the
  context of materials science. We find that crystallinity is a reliable me
 tric that varies across the brain along interpretable lines of anatomical 
 difference. We also parcellate white matter into ``crystal grains\," or co
 ntiguous sets of voxels of high structural similarity\, and find overlap w
 ith other white matter parcellations. Our results provide new means of ass
 essing white matter microstructure on multiple length scales\, and open ne
 w avenues of future inquiry.
LOCATION:https://zoom.us/j/92447982065?pwd=RkhaYkM5VTZPZ3pYSHptUXlRSkppQT0
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