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SUMMARY:Simulating cardiac fluid-structure interaction using the immersed 
 boundary method - Griffith\, B (New York)
DTSTART:20090722T131500Z
DTEND:20090722T133000Z
UID:TALK19170@talks.cam.ac.uk
CONTACT:Mustapha Amrani
DESCRIPTION:The immersed boundary (IB) method is a general mathematical fr
 amework and a particular numerical approach to problems of fluid-structure
  interaction. Over the last several years\, we have developed an adaptive 
 version of the IB method which uses Cartesian grid adaptive mesh refinemen
 t (AMR)\, thereby allowing us to deploy locally high spatial resolution wh
 ere it is most needed (e.g.\, in the vicinity of the heart valve leaflets 
 and the vorticies shed from those leaflets)\, and to use comparatively coa
 rse resolution where it suffices. In this talk\, we shall describe our ada
 ptive version of the IB method\, along with recent extensions of this meth
 od which enable the specification of physical boundary conditions for the 
 fluid\, thereby allowing us to connect three-dimensional immersed boundary
  models to reduced flow models (e.g.\, Windkessel models) via fluid bounda
 ry conditions. (Earlier versions of the IB method generally imposed period
 ic boundary conditions on the fluid\, and for such methods\, connections t
 o reduced flow models were mediated by internal fluid sources and sinks.) 
 Three-dimensional computational results will be presented to demonstrate t
 he application of this methodology to simulating the fluid mechanics of is
 olated models of heart valves\, as well as a new whole heart model derived
  from cardiac computed tomography (CT) data from a healthy human heart.
LOCATION:Seminar Room 1\, Newton Institute
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