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SUMMARY:Discovering the gene networks that regulate hunger - Katherine Law
 ler\, Research Associate Wellcome-MRC Institute of Metabolic Science\, Add
 enbrooke's Hospital
DTSTART:20230308T140000Z
DTEND:20230308T150000Z
UID:TALK192053@talks.cam.ac.uk
CONTACT:Samantha Noel
DESCRIPTION:ABSTRACT for 8th Mar 2023\, http://talks.cam.ac.uk/show/index/
 134146\n\nTitle: Discovering the gene networks that regulate hunger Studyi
 ng a rare disease with extreme clinical features can lead to new treatment
 s for patients\, and uncover underlying mechanisms involved in common diso
 rders and population health. The Genetics of Obesity Study (GOOS\, http://
 www.goos.org.uk ) recruited thousands of individuals with severe early-ons
 et childhood obesity and led to the identification of rare genetic variant
 s affecting key processes in the hypothalamus\, a part of the brain involv
 ed in appetite\, weight regulation and energy balance. To gain further ins
 ights our current work encompasses the genetics of rare severe childhood o
 besity and the genetics of thinness. We combine large genomic data sets fr
 om different populations and platforms with detailed clinical information 
 to discover new molecular pathways involved in appetite\, weight regulatio
 n and associated  disorders.\n\n\n
LOCATION:CMS\, Meeting Room 15
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