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SUMMARY:Force sensing across different length scales - from cell biology t
 o orthopaedic surgery - Prof. Sohini Kar-Narayan\, Department of Materials
  Science\, University of Cambridge
DTSTART:20221030T140000Z
DTEND:20221030T150000Z
UID:TALK192272@talks.cam.ac.uk
CONTACT:Fulvio Forni
DESCRIPTION:Functional nanomaterials can be integrated into force sensing 
 devices using advanced nanofabrication and microscale additive manufacturi
 ng techniques to create a range of versatile sensors\, including those aim
 ed at biomedical and clinical applications. For example\, a combination of
  aerosol-jet printing and 3d printing can be used to fabricate both bio-pi
 ezoelectric interfaces for sensing and stimulation of cells\, as well as f
 unctionalised conformable microfluidic force sensors for precision joint r
 eplacement surgery. The ability to control properties at the nanoscale thr
 ough processing allows for subsequent integration into functional devices 
 through additive manufacturing. To illustrate this\, I will focus of two s
 pecific case studies\, namely mechanosensing in cell biology using nanostr
 uctured polymer surfaces\, and microfluidic force sensing to enable precis
 ion orthopaedic surgery. In the first example\, I will discuss how biocomp
 atible poly l lactic acid (PLLA) nanotubes can provide a suitably ‘soft
 ’ surface for cell culture with controllable electromechanical propertie
 s\, and the implications this has for the field of mechanobiology. In the 
 second example\, I will discuss the development of novel conformable micro
 fluidic force sensors that aid in soft tissue balancing and implant positi
 oning during total hip arthroplasty\, thereby increasing the longevity of 
 hip replacements.\n\nThe seminar will be held in LR5 \, Baker Building\, D
 epartment of Engineering\, and online (zoom): https://us06web.zoom.us/j/87
 986687566?pwd=MGJScmMwd2lwT0tVMHNmWmxSa05XZz09
LOCATION:Department of Engineering / Online (Zoom)
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